Leave setting as their defaults for the first print.

Profiles: Print profiles are default settings at different layer heights. The lower the number the more layers, hence more detail, but at the cost of greater print time.

Note, different nozzle sizes will have different layer height ranges.

Infill: This is the amount of material the printer will deposit inside the print. Between 20-30% is ideal in most cases.

Other options can also be tweaked by clicking custom. Hovering over an option will give you a description of its purpose.

You may find you need to adjust certain settings to get your printer working perfectly, we recommend posting in the forum for the best advise on this.